consensus sequence

consensus sequence
Of a series of related DNA, RNA or protein sequences, the sequence that reflects the most common choice of base or amino acid at each position. Areas of particularly good agreement often represent conserved functional domains. The generation of consensus sequences has been subjected to intensive mathematical analysis.

Dictionary of molecular biology. 2004.

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  • consensus sequence — noun A DNA sequence found with minor variations and similar function in widely divergent organisms • • • Main Entry: ↑consensus …   Useful english dictionary

  • Consensus sequence — In molecular biology and bioinformatics, consensus sequence refers to the most common nucleotide or amino acid at a particular position after multiple sequences are aligned. A consensus sequence is a way of representing the results of a multiple… …   Wikipedia

  • consensus sequence — a sequence of nucleotides that is common to different genes or genomes, usually with some variations but showing substantial similarity; frequently, the prototype sequence that most others approach …   Medical dictionary

  • consensus sequence — The part of a gene or signal sequence that is shared over a wide range of members of a gene family, both within a given species, or in comparisons between species …   Glossary of Biotechnology

  • Kozak consensus sequence — The Kozak consensus sequence, Kozak consensus or Kozak sequence, is a sequence which occurs on eukaryotic mRNA and has the consensus (gcc)gccRccAUGG, where R is a purine (adenine or guanine) three bases upstream of the start codon (AUG), which is …   Wikipedia

  • Interferon Consensus Sequence-binding protein — (ICSBP) or Interferon Regulatory Factor 8 (IRF 8). It is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation. The critical role for ICSBP is in the decision for a Common Myeloid… …   Wikipedia

  • Sequence motif — In genetics, a sequence motif is a nucleotide or amino acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. For proteins, a sequence motif is distinguished from a structural motif, a motif formed …   Wikipedia

  • Sequence alignment — In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.[1]… …   Wikipedia

  • Consensus (disambiguation) — For the Wikipedia policy, see Wikipedia:Consensus. The word consensus may mean: 1992 Consensus Consensual nonconsent Consensus (computer science) achieving coherence, or quorum, among nodes of a distributed computer system. Consensus (medical)… …   Wikipedia

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